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1

Beneficial biological effects and the underlying mechanisms of molecular hydrogen - comprehensive review of 321 original articles -

Ichihara, Masatoshi, Sobue, Sayaka, Ito, Mikako, Ito, Masafumi, Hirayama, Masaaki, Ohno, Kinji

Journal:

Medical Gas Research

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

2

Simultaneous oral and inhalational intake of molecular hydrogen additively suppresses signaling pathways in rodents

Sobue, Sayaka, Yamai, Kazuaki, Ito, Mikako, Ohno, Kinji, Ito, Masafumi, Iwamoto, Takashi, Qiao, Shanlou, Ohkuwa, Tetsuo, Ichihara, Masatoshi

Journal:

Molecular and Cellular Biochemistry

Year:

2015

Language:

english

File:

PDF, 1.23 MB

english, 2015

3

Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters

Ito, Kenyu, Ohkawara, Bisei, Yagi, Hideki, Nakashima, Hiroaki, Tsushima, Mikito, Ota, Kyotaro, Konishi, Hiroyuki, Masuda, Akio, Imagama, Shiro, Kiyama, Hiroshi, Ishiguro, Naoki, Ohno, Kinji

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 7.56 MB

english, 2018

4

Molecular hydrogen upregulates heat shock response and collagen biosynthesis, and downregulates cell cycles – Meta-analyses of gene expression profiles −

Nishiwaki, Hiroshi, Ito, Mikako, Negishi, Shuto, Sobue, Sayaka, Ichihara, Masatoshi, Ohno, Kinji

Journal:

Free Radical Research

Year:

2018

Language:

english

File:

PDF, 627 KB

english, 2018

5

Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies

Mikako Ito, Tohru Ibi, Ko Sahashi, Masashi Ichihara, Masafumi Ito, Kinji Ohno

Journal:

Medical Gas Research

Year:

2011

Language:

english

File:

PDF, 158 KB

english, 2011

6

Molecular hydrogen suppresses FcεRI-mediated signal transduction and prevents degranulation of mast cells

Tomohiro Itoh, Yasunori Fujita, Mikako Ito, Akio Masuda, Kinji Ohno, Masatoshi Ichihara, Toshio Kojima, Yoshinori Nozawa, Masafumi Ito

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 902 KB

english, 2009

7

Significance of lymphatic invasion and cancer invasion-related proteins on lymph node metastasis in gastric cancer

Itaru Kamata, Yukio Ishikawa, Yuri Akishima-Fukasawa, Kinji Ito, Yoshikiyo Akasaka, Miwa Uzuki, Ai Fujimoto, Hiroshi Morita, Seiichi Tamai, Tadaaki Maehara, Kentaro Ogata, Reiko Shimokawa, Yoshinori I

Journal:

Journal of Gastroenterology and Hepatology

Year:

2009

Language:

english

File:

PDF, 521 KB

english, 2009

8

Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats

Muramatsu, Yukako, Ito, Mikako, Oshima, Takahiro, Kojima, Seiji, Ohno, Kinji

Journal:

Pediatric Pulmonology

Year:

2016

Language:

english

File:

PDF, 1.93 MB

english, 2016

9

Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice

Hasegawa, Satoru, Ito, Mikako, Fukami, Mayu, Hashimoto, Miki, Hirayama, Masaaki, Ohno, Kinji

Journal:

Year:

2016

Language:

english

File:

PDF, 1.57 MB

english, 2016

10

Basic fibroblast growth factor in an artificial dermis promotes apoptosis and inhibits expression of α-smooth muscle actin, leading to reduction of wound contraction

Yoshikiyo Akasaka, Ichiro Ono, Akihiro Tominaga, Yukio Ishikawa, Kinji Ito, Takeya Suzuki, Risa Imaizumi, Shigeki Ishiguro, Kowichi Jimbow, Toshiharu Ishii

Journal:

Wound Repair and Regeneration

Year:

2007

Language:

english

File:

PDF, 2.33 MB

english, 2007

11

Histopathologic determinants of regional lymph node metastasis in early colorectal cancer

Yukio Ishikawa, Yuri Akishima-Fukasawa, Kinji Ito, Yoshikiyo Akasaka, Tomoko Yokoo, Toshiharu Ishii, , the Toho Study Group for Cancer Biological Behavior

Journal:

Year:

2008

Language:

english

File:

PDF, 592 KB

english, 2008

12

Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases

Ohno, Kinji, Ito, Mikako, Ichihara, Masatoshi, Ito, Masafumi

Journal:

Oxidative Medicine & Cellular Longevity

Year:

2012

Language:

english

File:

PDF, 1.27 MB

english, 2012

13

Freeze-drying enables homogeneous and stable sample preparation for determination of fecal short-chain fatty acids

Ueyama, Jun, Oda, Masaya, Hirayama, Masaaki, Sugitate, Kuniyo, Sakui, Norihiro, Hamada, Risa, Ito, Mikako, Saito, Isao, Ohno, Kinji

Journal:

Analytical Biochemistry

Year:

2020

Language:

english

File:

PDF, 2.57 MB

english, 2020

14

Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages

Tomohiro Itoh, Nanako Hamada, Riyako Terazawa, Mikako Ito, Kinji Ohno, Masatoshi Ichihara, Yoshinori Nozawa, Masafumi Ito

Journal:

Biochemical and Biophysical Research Communications

Year:

2011

Language:

english

File:

PDF, 624 KB

english, 2011

15

Corrigendum to “Viral vector-mediated expression of human collagen Q in cultured cells” [Chem.-Biol. Interact. 175 (2008) 346–348]

Mikako Ito, Akio Masuda, Shinsuke Jinno, Takeshi Katagiri, Eric Krejci, Kinji Ohno

Journal:

Chemico-Biological Interactions

Year:

2009

Language:

english

File:

PDF, 77 KB

english, 2009

16

Fibromuscular dysplasia of coronary arteries resulting in myocardial infarction associated with hypertrophic cardiomyopathy in Noonan[apos ]s syndrome

Yukio Ishikawa, Kyoko Sekiguchi, Yoshikiyo Akasaka, Kinji Ito, Yuri Akishima, Lijun Zhang, Masamichi Itoh, Motoko Ishihara, Toshiharu Ishii

Journal:

Human Pathology

Year:

2003

Language:

english

File:

PDF, 312 KB

english, 2003

17

Mutations in the C-Terminal Domain of ColQ in Endplate Acetylcholinesterase Deficiency Compromise ColQ-MuSK Interaction

Nakata, Tomohiko, Ito, Mikako, Azuma, Yoshiteru, Otsuka, Kenji, Noguchi, Yoichiro, Komaki, Hirofumi, Okumura, Akihisa, Shiraishi, Kazuhiro, Masuda, Akio, Natsume, Jun, Kojima, Seiji, Ohno, Kinji

Journal:

Year:

2013

Language:

english

File:

PDF, 761 KB

english, 2013

18

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA

Rahman, Mohammad Alinoor, Masuda, Akio, Ohe, Kenji, Ito, Mikako, Hutchinson, David O., Mayeda, Akila, Engel, Andrew G., Ohno, Kinji

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 2.22 MB

english, 2013

19

Role of macrophage and smooth muscle cell apoptosis in association with oxidized low-density lipoprotein in the atherosclerotic development

Akishima, Yuri, Akasaka, Yoshikiyo, Ishikawa, Yukio, Lijun, Zhang, Kiguchi, Hideko, Ito, Kinji, Itabe, Hiroyuki, Ishii, Toshiharu

Journal:

Modern Pathology

Year:

2004

Language:

english

File:

PDF, 291 KB

english, 2004

20

[IEEE Mechatronics, 2007 IEEE International Conference on - Kumamoto University (2007.05.8-2007.05.10)] Mechatronics, 2007 IEEE International Conference on - Integrated Actuator-Sensor System on Patterned IPMC Film : Consideration of Electoric Interference

Nakadoi, Hyatt, Sera, Akio, Yamakita, Masaki, Asaka, Kinji, Luo, Zhi-Wei, Ito, Kazuhiko

Year:

2007

Language:

english

File:

PDF, 601 KB

english, 2007

21

Significance of Lymphatic Invasion on Regional Lymph Node Metastasis in Early Gastric Cancer Using LYVE-1 Immunohistochemical Analysis

Fujimoto, Ai, Ishikawa, Yukio, Akishima-Fukasawa, Yuri, Ito, Kinji, Akasaka, Yoshikiyo, Tamai, Seiichi, Maehara, Tadaaki, Kiguchi, Hideko, Ogata, Kentaro, Nishimura, Chiaki, Miki, Kazumasa, Ishii, Tos

Journal:

American Journal of Clinical Pathology

Year:

2007

Language:

english

File:

PDF, 445 KB

english, 2007

22

The acrolein cytotoxicity and cytoprotective action of α-tocopherol

Manabu Watanabe, Motonobu Sugimoto, Kinji Ito

Journal:

Journal of Gastroenterology

Year:

1992

Language:

english

File:

PDF, 979 KB

english, 1992

23

Patients with idiopathic cardiomyopathy belong to the same mitochondrial DNA gene family of Parkinson's disease and mitochondrial encephalomyopathy

Takayuki Ozawa, Masashi Tanaka, Satoru Sugiyama, Hidekazu Ino, Kinji Ohno, Kazuki Hattori, Toshihiro Ohbayashi, Takayuki Ito, Hirofumi Deguchi, Keishiro Kawamura, Yumiko Nakane, Kunitake Hashiba

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 578 KB

english, 1991

24

AP-1 Mediated Relief of Repressive Activity of the CD30 Promoter Microsatellite in Hodgkin and Reed-Sternberg Cells

Mariko Watanabe, Yuji Ogawa, Kinji Ito, Masaaki Higashihara, Marshall E. Kadin, Lawrence J. Abraham, Toshiki Watanabe, Ryouichi Horie

Journal:

The American Journal of Pathology

Year:

2003

Language:

english

File:

PDF, 518 KB

english, 2003

25

Endocrine and Immunohistochemical Studies on Thyrotropin (TSH)-Secreting Pituitary Adenomas: Responses of TSH, α -Subunit, and Growth Hormone to Hypothalamic Releasing Hormones and Their Distribution in Adenoma Cells

KUZUYA, NOBUAKI, INOUE, KINJI, ISHIBASHI, MIYUKI, MURAYAMA, YASUKO, KOIDE, YOSHINOBU, ITO, KUNIHIKO, YAMAJI, TOHRU, YAMASHITA, KAMEJIRO

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1990

Language:

english

File:

PDF, 1.86 MB

english, 1990

26

Recent advances in congenital myasthenic syndromes

Ohno, Kinji, Ohkawara, Bisei, Ito, Mikako

Journal:

Clinical and Experimental Neuroimmunology

Year:

2016

Language:

english

File:

PDF, 419 KB

english, 2016

27

Polynucleotide Ligase from Kidney Tumors in Rats Induced by N-Nitrosodimethylamine

TSUKADA, Kinji, ITO, Nobuyuki

Journal:

Journal of Biochemistry

Year:

1972

Language:

english

File:

PDF, 425 KB

english, 1972

28

Histiocytic sarcoma with fatal duodenal ulcers

Yuri Akishima, Yoshikiyo Akasaka, Ger Yih-Chang, Kinji Ito, Yukio Ishikawa, Zhang Lijun, Hideko Kiguchi, Gary Lipscomb, Jack P Strong, Toshiharu Ishii

Journal:

Pathology - Research and Practice

Year:

2004

Language:

english

File:

PDF, 472 KB

english, 2004

29

Steroid treatment increases the recurrence of radiation-induced organizing pneumonia after breast-conserving therapy

Otani, Keisuke, Nishiyama, Kinji, Ito, Yuri, Kawaguchi, Yoshifumi, Inaji, Hideo

Journal:

Cancer Medicine

Year:

2014

Language:

english

File:

PDF, 264 KB

english, 2014

30

Significance of Lymphatic Invasion and Proliferation on Regional Lymph Node Metastasis in Renal Cell Carcinoma

Ishikawa, Yukio, Aida, Shinsuke, Tamai, Seiichi, Akasaka, Yoshikiyo, Kiguchi, Hideko, Akishima-Fukasawa, Yuri, Hayakawa, Masamichi, Soh, Shigehiro, Ito, Kinji, Kimura-Matsumoto, Masayo, Ishiguro, Shig

Journal:

American Journal of Clinical Pathology

Year:

2007

Language:

english

File:

PDF, 6.91 MB

english, 2007

31

Lansoprazole Upregulates Polyubiquitination of the TNF Receptor-Associated Factor 6 and Facilitates Runx2-mediated Osteoblastogenesis

Mishima, Kenichi, Kitoh, Hiroshi, Ohkawara, Bisei, Okuno, Tatsuya, Ito, Mikako, Masuda, Akio, Ishiguro, Naoki, Ohno, Kinji

Journal:

Year:

2015

Language:

english

File:

PDF, 2.91 MB

english, 2015

32

Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms

Nazim, Mohammad, Masuda, Akio, Rahman, Mohammad Alinoor, Nasrin, Farhana, Takeda, Jun-ichi, Ohe, Kenji, Ohkawara, Bisei, Ito, Mikako, Ohno, Kinji

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 2.44 MB

english, 2016

33

ACTIN FILAMENT ALTERATIONS IN GLOMERULAR EPITHELIAL CELLS OF ADRIAMYCIN-INDUCED NEPHROTIC RATS

Kinji Ito, Yih-Chang Ger, Sadao Kawamura

Journal:

Pathology International

Year:

1986

Language:

english

File:

PDF, 1.86 MB

english, 1986

34

Urinary 8-hydroxydeoxyguanosine correlate with hallucinations rather than motor symptoms in Parkinson’s disease

Masaaki Hirayama, Tomohiko Nakamura, Hirohisa Watanabe, Kei Uchida, Tetsuo Hama, Takashi Hara, Yoshiki Niimi, Mizuki Ito, Kinji Ohno, Gen Sobue

Journal:

Parkinsonism & Related Disorders

Year:

2011

Language:

english

File:

PDF, 152 KB

english, 2011

35

Protein-anchoring Strategy for Delivering Acetylcholinesterase to the Neuromuscular Junction

Ito, Mikako, Suzuki, Yumi, Okada, Takashi, Fukudome, Takayasu, Yoshimura, Toshiro, Masuda, Akio, Takeda, Shin'ichi, Krejci, Eric, Ohno, Kinji

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 448 KB

english, 2012

36

Differential effects of spinal motor neuron-derived and skeletal muscle-derived Rspo2 on acetylcholine receptor clustering at the neuromuscular junction

Li, Jin, Ito, Mikako, Ohkawara, Bisei, Masuda, Akio, Ohno, Kinji

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.21 MB

english, 2018

37

InMeRF: prediction of pathogenicity of missense variants by individual modeling for each amino acid substitution

Takeda, Jun-ichi, Nanatsue, Kentaro, Yamagishi, Ryosuke, Ito, Mikako, Haga, Nobuhiko, Hirata, Hiromi, Ogi, Tomoo, Ohno, Kinji

Journal:

NAR Genomics and Bioinformatics

Year:

2020

File:

PDF, 3.36 MB

2020

38

NER Rat Strain: A New Type of Genetic Model in Epilepsy Research

Atsushi Noda, Ryoichi Hashizume, Toshiro Maihara, Yasuhiro Tomizawa, Yoshihiko Ito, Maki Inoue, Kinji Kobayashi, Yuzo Asano, Masashi Sasa, Tadao Serikawa

Journal:

Year:

1998

Language:

english

File:

PDF, 1.07 MB

english, 1998

39

Multiple mitochondrial DNA deletions exist in cardiomyocytes of patients with hypertrophic or dilated cardiomyopathy

Takayuki Ozawa, Masashi Tanaka, Satoru Sugiyama, Kazuki Hattori, Takayuki Ito, Kinji Ohno, Akira Takahashi, Wataru Sato, Goro Takada, Bunji Mayumi, Kiichiro Yamamoto, Kyo Adachi, Yoshinori Koga, Hiron

Journal:

Biochemical and Biophysical Research Communications

Year:

1990

Language:

english

File:

PDF, 1.38 MB

english, 1990

40

Significance of Lymphatic Invasion on Regional Lymph Node Metastasis in Early Gastric Cancer Using LYVE-1 Immunohistochemical Analysis

Fujimoto, Ai, Ishikawa, Yukio, Akishima-Fukasawa, Yuri, Ito, Kinji, Akasaka, Yoshikiyo, Tamai, Seiichi, Maehara, Tadaaki, Kiguchi, Hideko, Ogata, Kentaro, Nishimura, Chiaki, Miki, Kazumasa, Ishii, Tos

Journal:

American Journal of Clinical Pathology

Year:

2007

Language:

english

File:

PDF, 445 KB

english, 2007

41

Four parameters increase the sensitivity and specificity of the exon array analysis and disclose 25 novel aberrantly spliced exons in myotonic dystrophy

Yamashita, Yoshihiro, Matsuura, Tohru, Shinmi, Jun, Amakusa, Yoshinobu, Masuda, Akio, Ito, Mikako, Kinoshita, Masanobu, Furuya, Hirokazu, Abe, Koji, Ibi, Tohru, Sahashi, Koo, Ohno, Kinji

Journal:

Journal of Human Genetics

Year:

2012

Language:

english

File:

PDF, 491 KB

english, 2012

42

Roles of collagen Q in MuSK antibody-positive myasthenia gravis

Ohno, Kinji, Otsuka, Kenji, Ito, Mikako

Journal:

Chemico-Biological Interactions

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

43

Molecular hydrogen suppresses activated Wnt/β-catenin signaling

Lin, Yingni, Ohkawara, Bisei, Ito, Mikako, Misawa, Nobuaki, Miyamoto, Kentaro, Takegami, Yasuhiko, Masuda, Akio, Toyokuni, Shinya, Ohno, Kinji

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.86 MB

english, 2016

44

Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy

Chen, Guiying, Masuda, Akio, Konishi, Hiroyuki, Ohkawara, Bisei, Ito, Mikako, Kinoshita, Masanobu, Kiyama, Hiroshi, Matsuura, Tohru, Ohno, Kinji

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.64 MB

english, 2016

45

10.2208/prooe.20.1187

ITO, Masahiro, OOE, Kinji, KOJIMA, Kazuya, YAMASHITA, Takao

Journal:

PROCEEDINGS OF CIVIL ENGINEERING IN THE OCEAN

Year:

2004

File:

PDF, 1.01 MB

2004

46

Tumor Necrosis Factor Receptor-associated Factor (TRAF) 5 and TRAF2 Are Involved in CD30-mediated NFÎºB Activation

Aizawa, Shigemi, Nakano, Hiroyasu, Ishida, Takaomi, Horie, Ryouichi, Nagai, Masae, Ito, Kinji, Yagita, Hideo, Okumura, Ko, Inoue, Junichiro, Watanabe, Toshiki

Journal:

Journal of Biological Chemistry

Year:

1997

File:

PDF, 337 KB

1997

47

Activated caspase expression and apoptosis increase in keloids: cytochrome c release and caspase-9 activation during the apoptosis of keloid fibroblast lines

Yoshikiyo Akasaka, Kinji Ito, Kazuko Fujita, Kazuo Komiyama, Ichiro Ono, Yukio Ishikawa, Yuri Akishima, Hiroko Sato, Toshiharu Ishii

Journal:

Wound Repair and Regeneration

Year:

2005

Language:

english

File:

PDF, 1.57 MB

english, 2005

48

Simultaneous determination of halogenated benzene compouds by mass chromatography.

ITO, Hiroyasu, YASUHARA, Akio, MORITA, Masatoshi, MIZOGUCHI, Tsuguo, GONDA, Kinji

Journal:

Year:

1990

File:

PDF, 675 KB

1990

49

Myocardial apoptosis associated with the expression of proinflammatory cytokines during the course of myocardial infarction

Akasaka, Yoshikiyo, Morimoto, Noriko, Ishikawa, Yukio, Fujita, Kazuko, Ito, Kinji, Kimura-Matsumoto, Masayo, Ishiguro, Shigeki, Morita, Hiroshi, Kobayashi, Yoshiro, Ishii, Toshiharu

Journal:

Modern Pathology

Year:

2006

Language:

english

File:

PDF, 515 KB

english, 2006

50

DISTRIBUTION OF ACTIN IN MESANGIAL CELL OF RAT GLOMERULUS

Kinji Ito, Yih-Chang Ger

Journal:

Pathology International

Year:

1984

Language:

english

File:

PDF, 988 KB

english, 1984

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